Chase Suno and his friends, Jinja and Bren, are on a search for Chase's father, Jeredy Suno. However, they soon become involved in something else upon reaching their father's lab and becoming involved with an organism known as Monsuno. Chase, choosing to side with his father's work, denies S.T.O.R.M. access to the Monsuno and escapes. They are now on the run from the military organization, S.T.O.R.M., while still looking for Chase's father. However, a mysterious organization also has his eyes set on Chase and the group's Monsuno.

Chase Suno and his friends, Jinja and Bren, are on a search for Chase's father, Jeredy Suno. However, they soon become involved in something else upon reaching their father's lab and becoming involved with an organism known as Monsuno. Chase, choosing to side with his father's work, denies S.T.O.R.M. access to the Monsuno and escapes. They are now on the run from the military organization, S.T.O.R.M., while still looking for Chase's father. However, a mysterious organization also has his eyes set on Chase and the group's Monsuno.

Chase Suno and his friends, Jinja and Bren, are on a search for Chase's father, Jeredy Suno. However, they soon become involved in something else upon reaching their father's lab and becoming involved with an organism known as Monsuno. Chase, choosing to side with his father's work, denies S.T.O.R.M. access to the Monsuno and escapes. They are now on the run from the military organization, S.T.O.R.M., while still looking for Chase's father. However, a mysterious organization also has his eyes set on Chase and the group's Monsuno.

Chase Suno and his friends, Jinja and Bren, are on a search for Chase's father, Jeredy Suno. However, they soon become involved in something else upon reaching their father's lab and becoming involved with an organism known as Monsuno. Chase, choosing to side with his father's work, denies S.T.O.R.M. access to the Monsuno and escapes. They are now on the run from the military organization, S.T.O.R.M., while still looking for Chase's father. However, a mysterious organization also has his eyes set on Chase and the group's Monsuno.

In the year 3990, the immortal Oldna Poseidal rules Pentagona, a war-torn solar system of five planets. Daba Myroad is a survivor of the Yaman Clan, just one of numerous native societies nearly wiped out by the tyrant. Living on the remote planet Koam with his friend Mirao Kyao, Daba possesses L-Gaim, a humanoid mecha known commonly as a "Heavy Metal" and the last known relic of the Yaman Clan. The pair befriend Fanneria Amu, an aspiring actress, and Lilith Fau, the last surviving fairy in Pentagona while on the run from a band of thieves attempting to steal L-Gaim. Daba promises to fulfill the dying wish of one of the thieves hunting him—an honorable act that leads him to the powerful merchant Amandara Kamandara. With their mission in sight, the ragtag group will face powerful adversaries and become entangled in a rebellion against Poseidal's reign.

A recap OVA that portrays the first half of the series Heavy Metal L-Gaim. After the credits, there is a short clip animated for the OVA entitled "Lady Gavlet", which is intended to be comic relief.

A recap OVA that portrays the second half of the series Heavy Metal L-Gaim. After the credits, there is a short clip animated for the OVA entitled "Pentagona Dolls", which is intended to be comic relief.

A side story taking place somewhere before the second half of the series, prior to Daba acquiring the L-Gaim Mk-II. Daba's comrade Leccee is captured by Poseidal's forces, and Daba and his rebels attempt to save her.

The world we live in is called Earthside in this story. There are the other worlds called Nosfertia, Heavenstia, and Eternalia. When Darknoids from Nosfertia begun invasion to Earthside, Heavenstia sent 3 Animanoids (beast-humans) to prevent it. The lead character Touya had believed that he was a mere human but found he was actually a being of Eternalia. With the help of 3 Animanoids, Touya fights to defend Earthside.

Set in a time of chaos, seven heroes of the Stars, the Hokushintenkun, rise up to lead the people. Two of the seven, the Nitenshinson, the Hagun and the Tonrou, are never supposed to exist at the same time, but fate has decided otherwise. Taito, chosen as the Hagun, now must rise up to defeat the Tonrou, as the fate of the Stars destined it to be.

It is 199X A.D. In Kushiro, Hokkaido, three bodies of Dragonite appear. Possessing overwhelming destructive force, they attack the city. They also awaken the evil Jashin Drago from the holy seal he was trapped in. 200 years ago, Drago was trapped in the seal by a holy warrior with the tattooed mark of the Liger. Assuming that the warrior is dead, Drago and Empress Zara are free to conquer the Earth using their army of biomechanical beasts. Even the Japan Self-Defense Forces are no match for the Dragonites' awesome power. One of the people fleeing is the protagonist, a milquetoast 16 year old boy named Ken Taiga. Unbeknownst to the Dragonites, Ken realizes that he is the descendant of the Liger warrior! In a burst of anger, Ken's Liger birthmark appears, and he rises his palm into the air, shouting the henshin command, "LIGER!!!", which then covers him in demonic long-haired biomechanical armor. Ken transforms into Jushin Liger to fight the evil forces of the Dragonite!

The new series is set in a near-future world where the boundary between human being and AI is vague. A rapid biological evolution, similar to "Cambrian Explosion," is caused by one incident. This incident turns into the genesis of a new jostle for supremacy, and the influence of the evolution goes beyond biological framework and spreads to various kinds of materials and technologies. The era of massive evolution involving diverse existences, such as human, machines, and biotechnologies, is coming. Characters fight an existential war in such a world.